Skip to main content
Banner [Small]

Test out our new Bento Search

test area
x
# results
shortcut
Sections
HTML elements
Section Tiles
expand
Tile Cover
Mouse
Math Lab
Space
Tile Short Summary
Math Lab Rooms located in the Main Library in rooms 300X and 300Y
expand
Tile Cover
coffee
CC's Coffee House
Space
Tile Short Summary
Located at the first floor of the LSU Main Library.
expand
Tile Cover
People troubleshooting on a computer
Ask Us
Service
Tile Short Summary
Check our FAQs, submit a question using our form, or launch the chat widget to find help.

Website

207

Gear

44

FAQ

169

Staff

101

Discovery

2062430
Executive functions and associated brain volumetry in children with persistent stunting and catch-up growth
Abstract Early childhood stunting can result in sub-optimal executive functions (EF), affecting academic achievements and economic potential in later life. This study hypothesized that children always stunted (AS) at ages 2, 5 and 9 years had lower EF than those who were never stunted (NS). A birth-cohort in Vellore, India was followed up with periodic anthropometric and development/cognitive measures over 2, 5 and 9 years of age. Based on stunting status at these time points, children were classified as NS, stunted at 2 years and caught up by 5 years (S2N5), stunted at 2 and 5 years but caught up later (S5N9), and AS. At 9th year, children underwent neuroimaging using 3T MRI scanner and EF assessment using FAS phonemic fluency test, colour cancellation test and colour trials tests (CTT). From the original birth-cohort of 251, 205 children were reviewed at 9 years. FAS phonemic fluency test showed NS group had significantly higher test scores compared to AS (11.52 vs. 7.4, p = 0.02). In CTT, a significant difference in near misses score was observed between NS and AS groups (0.12 vs. 0.38, p = 0.03). Upon evaluating unimodal brain association areas, volumes of right occipital fusiform gyrus (9991 mm3 vs. 9313 mm3; p = 0.04; η2 = 0.11), and left lateral occipital cortex (13458 mm3 vs. 12559 mm3; p = 0.03; η2 = 0.07) were significantly higher among NS compared to AS group. Considering higher order association areas, only left pars triangularis was found to be significantly reduced among AS children compared to NS group (4284 mm3 vs. 3291 mm3; p = 0.01; η2 = 0.07). Similarly, there were also significance visible in the basal ganglia regions and the cerebellum. Current study demonstrated EF dysfunction in verbal fluency and inhibitory control in a dose response fashion in groups AS-to-NS with corresponding EF-related brain volumetric changes, highlighting the need for focused nutritional and nurturing approaches in early childhood for gain in human capital.
Impact of climate change on global catches of marine fisheries from 1971 to 2020
Marine fisheries catches have significant economic, social, and cultural importance for coastal communities and nations worldwide. In addition to overfishing and predation, oceanic conditions linked to climate variability profoundly affect catches of oceanic fish species. Based on the fishery data from the Food and Agriculture Organization (FAO) of the United Nations and multiple physical and biogeochemical datasets, we examined the correlation between major modes of climate variability at high and low frequency and multiple key fish species in five major fishing grounds worldwide. The results reveal that over 80% of selected key fish species have declined over the past five decades, with more than 50% transitioning from an increasing to a decreasing trend in the 1990s. Additionally, over 80% of fish species directly correlate with low-frequency climate indices, including Pacific Decadal Oscillation (PDO), Atlantic Multi-decadal Oscillation (AMO) and tropical southern Atlantic (TSA). However, less than 40% of fish species exhibit a direct association with high-frequency climate indices of El Niño Southern Oscillation (ENSO), North Atlantic Ocean (NAO), and Atlantic Niño (ATL3). Synthetic analysis on the Sea Surface Temperature (SST), Mixed Layer Depth (MLD) and chlorophyll a revealed that shifts in the low-frequency climate can directly affect the habitats of numerous fish species, and subsequently influence their fishing yields. Specially, negative SST anomalies and positive chlorophyll-a anomalies were observed during a positive phase of PDO in the central and western Pacific regions, resulting in an increased catch values of Alaska pollock, Pacific sardine, and Chilean jack mackerel. Similar changes occur in positive and negative phases of other low frequency indices. Our research offered a comprehensive perspective on oceanic fish catch responses to climate change, serving as a guide for formulating effective management strategies for marine fish resources.
Cord Blood Exosomal miRNAs from Small-for-Gestational-Age Newborns: Association with Measures of Postnatal Catch-Up Growth and Insulin Resistance.
Small-for-gestational-age (SGA) infants who experience a marked postnatal catch-up, mainly in weight, are at risk for developing metabolic disorders; however, the underlying mechanisms are imprecise. Exosomes and their cargo (including miRNAs) mediate intercellular communication and may contribute to altered crosstalk among tissues. We assessed the miRNA profile in cord blood-derived exosomes from 10 appropriate-for-gestational-age (AGA) and 10 SGA infants by small RNA sequencing; differentially expressed miRNAs with a fold change ≥2.4 were validated by RT-qPCR in 40 AGA and 35 SGA infants and correlated with anthropometric, body composition (DXA) and endocrine–metabolic parameters at 4 and 12 mo. miR-1-3p, miR-133a-3p and miR-206 were down-regulated, whereas miR-372-3p, miR-519d-3p and miR-1299 were up-regulated in SGA infants. The target genes of these miRNAs related to insulin, RAP1, TGF beta and neurotrophin signaling. Receiver operating characteristic analysis disclosed that these miRNAs predicted with accuracy the 0–12 mo changes in body mass index and in total and abdominal fat and lean mass. In conclusion, the exosomal miRNA profile at birth differs between AGA and SGA infants and associates with measures of catch-up growth, insulin resistance and body composition through late infancy. Further follow-up of this population will disclose whether these associations persist into childhood, puberty and adolescence. [ABSTRACT FROM AUTHOR]
Association of weekend catch-up sleep ratio with depressive risk: insights from NHANES 2021–2023.
Background: Depression is a common global mental health issue, affecting around 3.8% of the population. It significantly impacts quality of life and social functioning, posing a major public health challenge. Sleep is a key factor influencing depression, with both sleep quality and quantity linked to mental health. However, sleep deprivation is widespread, and many people compensate by "weekend sleep recovery." The effects of sleep deprivation and weekend recovery on depression risk are unclear, as irregular sleep patterns may worsen depressive symptoms. This study introduces the "Weekend Catch-up Sleep Ratio" (CUS ratio) to better understand the relationship between sleep patterns and depression. Methods: Cross-sectional data were obtained from individuals who participated in the 2021–2023 National Health and Nutrition Examination Survey (NHANES) and had complete data on CUS and the Patient Health Questionnaire (PHQ-9). Multivariable logistic regression was performed to assess the potential independent association between depression and the CUS ratio. Additionally, smoothing curve fitting, threshold effect analysis, subgroup analysis, and interaction tests were conducted. Results: A total of 4,656 individuals were analyzed, categorized by depression symptoms (PHQ-9 score of 10 or higher), with an overall depression risk of 12.4%. In the adjusted model, the CUS ratio was significantly positively associated with depression risk (AOR = 1.75, 95% CI: 1.25–2.45), exhibiting a nonlinear threshold effect (inflection point at 1.11). When the CUS ratio ≤ 1.11, an increase in the ratio was associated with a reduced depression risk (AOR = 0.34, 95% CI: 0.13–0.89), whereas when the CUS ratio > 1.11, each unit increase in the ratio significantly increased depression risk by 187% (AOR = 2.87, 95% CI: 1.84–4.50). Individuals with education levels of less than 9th grade, some college or an Associate of Arts (AA) degree, those who are overweight (25 ≤ BMI < 30), and those without diabetes appeared more sensitive to fluctuations in sleep patterns. In the adjusted model for the severity of depressive symptoms, the CUS ratio was significantly positively associated with depression severity (Aβ = 0.19, 95% CI: 0.09–0.28), also exhibiting a nonlinear threshold effect (inflection point at 1.11). When the CUS ratio ≤ 1.11, an increase in the ratio was associated with a reduction in depression severity (Aβ = -0.35, 95% CI: -0.62 to -0.09), whereas when the CUS ratio > 1.11, each unit increase in the ratio significantly increased depression severity (Aβ = 0.36, 95% CI: 0.24–0.49). In particular, individuals without diabetes appeared more sensitive to fluctuations in sleep patterns. Conclusions: This study suggests that maintaining a balanced sleep pattern, with a CUS ratio between 1 and 1.11, may help reduce depression risk and promote better mental health. [ABSTRACT FROM AUTHOR]
Ground testing and calibration of focal plane detector flight model on board the first pathfinder of CATCH
CATCH-1, as the first satellite of Chasing All Transients Constellation Hunters (CATCH) space mission, was successfully launched into its expected orbit on June 22, 2024. The flight model underwent environmental tests before launch, including thermal cycling, thermal vacuum, and mechanical evaluations. The CATCH-1 detector system is equipped with a 4-pixel Silicon Drift Detector (SDD) array. To ensure the reliability and redundancy of the CATCH-1 detector system, two sets of data acquisition systems were independently designed and calibrated. Our focus is on presenting the ground calibration results of CATCH-1, which demonstrate a strong linear correlation between energy and channel. The main data acquisition system achieves an energy resolution of ∼≤∼4μs≤10μs 120 eV@4 keV, while the backup data acquisition system has a slightly lower energy resolution of around 150 eV@4 keV, both meeting the design requirement of ∼≤∼4μs≤10μs 160 eV@4 keV. Additionally, the time resolution is ∼≤∼4μs≤10μs, complying with the design requirement of ∼≤∼4μs≤10μs. The calibration database now includes the ground calibration results of CATCH-1, establishing a dependable basis for future data analysis. The development experience, calibration, and test results of this detector system will also provide a solid foundation for subsequent tasks such as CATCH-2.