No summary available.

Purpose To compare optic nerve head (ONH) surface change detection by confocal scanning laser tomography (CSLT) within the LSU Experimental Glaucoma (LEG) study to expert clinicians viewing the LEG stereophotographs.Design Experimental study.Participants Four fellowship-trained glaucoma specialists.Methods In the LEG study, six 15° CSLT images (TopSS, Laser Diagnostics Technologies, San Diego, CA) and four 2× optic disc stereophotographs were obtained from both eyes of 12 monkeys on 3 separate days and then every 2 weeks after laser to one eye (study eye) to elevate intraocular pressure. ONH surface change detection within the CSLT images is described in our companion report. In this report, the preliminary study compared change detection by the CSLT multivariate strategy with that of a single clinician viewing stereophotograph pairs on three separate occasions as the “gold standard.” The main study compared change detection by three additional clinicians viewing a subset of LEG stereophotograph pairs on three separate occasions with that of the CSLT multivariate strategy as the “gold standard.” Clinician change detection was assessed for partial (two of three occasions) or complete (three of three occasions) agreement. Three comparison groups within the main study are emphasized: 44 group A comparisons assessed false-positive change detection (specificity); 38 group B comparisons assessed change detection within 38 instances (11 onset and 27 progression events) of CSLT-detected study eye change; and 30 group C comparisons assessed change detection within 30 instances in which the CSLT failed to detect change in study eyes.Main outcome measures Clinician change detection within each comparison with either partial or complete agreement.Results Within the main study, intrareading (−.29 to 0.67) and interreading (0.24–0.56) session agreement for each clinician was slight to moderate by kappa test. Good specificity (less than 10% false-positive change detection) was achieved within the 44 group A comparisons by two of the three clinicians, but only when the more stringent criterion (change detection on three of three occasions) was applied. Of the 38 group B comparisons (in which the CSLT detected change), the two clinicians who achieved good specificity in group A failed to detect change in 25 and 16 instances, respectively, using the more stringent (three of three) criterion. Similarly, of the 30 group C comparisons (in which the CSLT failed to detect change), these two clinicians detected change in three and seven instances, respectively, but in only one comparison did they both detect change.Conclusions This study provides the first direct evidence that an existing CSLT may reasonably meet or exceed the ONH surface change detection performance of fellowship-trained glaucoma specialists in at least those eyes with good CSLT reproducibility.

Byline: Guardian sport Louisiana's Republican governor has called for the scholarships of college athletes who are not present for the playing of the national anthem to be revoked after the […]

Byline: Steve Gardner, USA TODAY After some scathing criticism from LSU women's basketball coach Kim Mulkey, the Los Angeles Times has updated a column it published before Saturday's LSU-UCLA matchup […]

CLEMSON - Delta is adding flights from Greenville-Spartanburg International Airport to help Clemson University fans travel to Baton Rouge for the big game against Louisiana State University. The high-profile football matchup will see Coach Dabo Swinney lead the Clemson Tigers against the LSU Tigers in Lane Kiffin's first year as head coach. The new flights are part of more than 40 nonstop flights Delta is adding to its schedule to accommodate college football season...

Golden State Valkyries general manager Ohemaa Nyanin didn't have much to say on Monday when she was asked about her decision to trade LSU star Flau'jae Johnson. The Valkyries, an expansion team beginning its second season in the WNBA, selected Johnson with the eighth overall pick of Monday's WNBA draft, then flipped her to the Seattle Storm for a 2028 second-round choice and the right to take Marta Suarez of TCU with the 16th pick. Nyanin told ESPN Monday night that the two teams had agreed to the trade before either of the picks was made. "I want to be...