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Are there any graduate assistantships available?
Most assistantships would be found on the LSU Handshake website (https://www.lsu.edu/careercenter/students/handshake.php) , though some opportunities are handled directly through the hiring department. It wouldn't hurt to check with a staff member in your graduate program to see if they are aware of assistantships not listed on Handshake. ________________________________________________________________________ More information on Handshake.... How to Access Handshake Admitted Students Undergraduate and Graduate students receive access to Handshake on June 15. At that time, you can log in to Handshake using your myLSU email and password at lsu.joinhandshake.com (https://lsu.joinhandshake.com/) or download the Handshake Jobs & Careers App (download in the Apple App Store (https://apps.apple.com/app/apple-store/id1220620171) or download through Google Play (https://play.google.com/store/apps/details?id=com.joinhandshake.student…) ). If a user experiences a barrier in access to Handshake or content within due to a disability, please contact the LSU Olinde Career Center at career@lsu.edu (mailto:career@lsu.edu) . For information on how to apply to on-campus and off-campus jobs, visit the Student Employment webpage (https://www.lsu.edu/careercenter/studentemployment/students.php) . If you would like to schedule a meeting with our team, or access other career center resources prior to receiving Handshake access, please contact us at career@lsu.edu (mailto:career@lsu.edu) and we are happy to assist you. Graduate Students: Please note, while some graduate assistantships may be posted in Handshake, most opportunities are managed directly through the hiring department. Please contact your graduate program and campus contacts directly to inquire about available assistantships. Alumni Alumni retain free access to Handshake and to most other career center resources, including appointments with the career center team. View the Alumni Resources page to request Handshake access (https://www.lsu.edu/careercenter/students/alumni.php) . Rsum Uploads Please make note that all rsums must be approved by the LSU Olinde Career Center before becoming active in Handshake for applying for jobs or participating in on-campus interviews. Please be prompt in submitting a rsum for activation in Handshake. The career center makes every effort to be timely in the document approval process, but cannot guarantee a turnaround of less than two (2) business days. Fraudulent and Scam Job Postings We work hard to keep fraudulent postings out of Handshake (https://www.lsu.edu/careercenter/students/handshake.php) by using some common red flags typically considered suspicious. While red flags dont automatically remove a job posting, we research the company and posting if suspicion arises before making a decision. You should research suspicious companies or postings, too (or dont apply). The Fraudulent and Scam Job Postings (https://www.lsu.edu/careercenter/about/FraudulentandScamJobPostingsbook…) guide outlines red flags so you, too, can attempt to identify such scam or fraudulent postings. Our position: Never apply for a suspicious job. Questions? Contact career@lsu.edu (mailto:career@lsu.edu) . Answered by: Gabriella Lindsay

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The C-terminal actin-binding domain of talin forms an asymmetric catch bond with F-actin
Focal adhesions (FAs) are large, integrin-based protein complexes that link cells to the extracellular matrix (ECM). FAs form only when and where they are necessary to transmit force between the cellular cytoskeleton and the ECM, but how this occurs remains poorly understood. Talin is a 270-kDa adaptor protein that links integrins to filamentous (F)-actin and recruits additional components during FA assembly in a force-dependent manner. Cell biological and developmental data demonstrate that the third and C-terminal F-actin–binding site (ABS3) of talin is required for normal FA formation. However, purified ABS3 binds F-actin only weakly in solution. We used a single molecule optical trap assay to examine how and whether ABS3 binds F-actin under physiologically relevant mechanical loads. We find that ABS3 forms a catch bond with F-actin when force is applied toward the pointed end of the actin filament, with binding lifetimes >100-fold longer than when force is applied toward the barbed end. Long-lived bonds to F-actin under load require the ABS3 C-terminal dimerization domain, whose cleavage has been reported to regulate FA turnover. Our results support a mechanism in which talin ABS3 preferentially binds to and orients actin filaments with barbed ends facing the cell periphery, thus nucleating long-range order in the actin cytoskeleton. We suggest that talin ABS3 may function as a molecular AND gate that allows FA growth only when sufficient integrin density, F-actin polarization, and mechanical tension are simultaneously present.